Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. N-debenzoyl-(3'-RS)-taxol + benzoyl-CoA -> taxol + coenzyme A + H+ PlantCyc CPD-8718 from the stem bark of Taxus brevifolia and Taxus cuspidata (Taxaceae) Zerenex MolecularĪDCs cytotoxin Microtubule/Tubulin MedChem Express HY-B0015Īntibody-drug conjugates/ADCs Related MedChem Express HY-B0015Īntibody-drug conjugates/ADCs Related Cell Cycle/DNA Damage MedChem Express HY-B0015 Name 'taxol' is now limited, as Taxol is a registered trade mark. It is a mitotic inhibitor used in cancer chemotherapy.
ChEBI CHEBI:45863Ī tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. Note that the use of the formĮr generic name 'taxol' is now limited, as Taxol is a registered trade mark.
Chemical Class: A tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. OU Chemical Safety Data (No longer updated) More details Organic Compound Amine Ether Ester Drug Antineoplastic Agent, Phytogenic Tubulin Modulator Plant Toxin Metabolite Natural Compound Toxin, Toxin-Target Database T3D4019 Toxicity: IPR-RAT LD50 33 mg kg-1, IPR-MUS LD50 128 mg kg-1 OU Chemical Safety Data (No longer updated) More details. Incompatible with strong oxidizing agents. Appearance: white crystalline powder OU Chemical Safety Data (No longer updated) More details. 
Experimental Solubility: 10 mM in H2O MedChem Express HY-B0015.Experimental Boiling Point: 957.1 ☌ Cayman Chemical (old) CM110346.
Experimental Melting Point: 213-216 ☌ OU Chemical Safety Data (No longer updated) More detailsĢ14.5 ☌ Jean-Claude Bradley Open Melting Point Dataset 14775, 16370Ģ16.5 ☌ Jean-Claude Bradley Open Melting Point Dataset 28375Ģ13 ☌ (Decomposes) Matrix Scientific 096914Ģ13 ☌ (Decomposes) Sigma-Aldrich USP-1491332. Experimental Physico-chemical Properties. The Google Patents add-in will initiate an exact or substructure search into Google Patents and/or Google Scholar. Select molecules and get immediate insight into their potential applications. Export collections as Powerpoint Slides in one click or as an SD File. Create lists of compounds, edit chemical structures and annotate them easily. ChemOffice+ lets you browse, extract and re-use ChemDraw® documents embedded inside MS Office documents. The new Cloud application designed to facilitate the communication of Chemistry. Upon 1st launch of ChemDraw 20.0, a comprehensive hotkey cheat sheet will be presented to the user.Ĭomplementary to the version 19.0 Ring Fill coloring, atoms, labels and bonds can highlighted with a specific color to facilitate communication and audience focus.Ī new 3D clean-up function will generate 3D confirmations of structures from 2D representations, to generate realistic 3D renderings in just a few clicks “Shift+o” creates a “OMe” group, and “Shift+e” a “CO2Me”. “k” now creates a sulfone group, “Shift+k” on primary carbon gives a tert-butyl group with 90° angles and on secondary carbons a wedged/hashed-wedged gem-dimethyl group. Here are some of the highlights of version 20.0:Ī new Molecule hotkey “Enter” is available to switch from a selected molecule to hotspot molecule editing.
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